2,4-Difluoro-α-(1H-1,2,4-triazolyl)acetophenone/ DFTA

Product Description

• It is used in the synthesis of azole-based antifungal drugs like fluconazole and voriconazole.
• It also shows antifungal activity, particularly against Candida albicans and Candida parapsilosis.
• The primary use of DFTA is as a precursor for the synthesis of azole-based antifungal medications, including fluconazole and voriconazole. 
  • Fluconazole synthesis: DFTA is a key intermediate in the chemical pathway to producing fluconazole. It provides a triazole ring, a crucial part of the final bioactive drug structure.
  • Voriconazole synthesis: It is also used in the manufacturing process for voriconazole. Some pharmacopoeias, like the United States Pharmacopeia (USP), identify DFTA as "Voriconazole Related Compound C". 

Product Highlights

• High-Purity Intermediate: Ensures reliable pharmaceutical outcomes

• Critical for Oncology: Essential for hormone-responsive breast cancer drugs

• Stable Structure: Suitable for large-scale API production

• Trusted in Pharma: Widely used in oncology-related formulations

• Reliable Performance: Consistent results in pharmaceutical manufacturing

End Uses

• Pharmaceutical Intermediate: Key intermediate in the synthesis of Fluconazol

Safety & Handling

• Store in a cool, dry environment away from direct light

• Avoid inhalation, ingestion, and prolonged skin contact

• Use protective clothing, gloves, and safety goggles during handling

• Dispose of waste according to pharmaceutical regulations