Packaging Details
The primary application of 4-chlorobenzhydryl piperazine (Norchlorcyclizine, CAS 303-26-4) is as a key pharmaceutical intermediate for synthesizing several important drugs. It is not typically used as an active ingredient itself but as a crucial building block in manufacturing other complex molecules.
Key applications include:
Synthesis of Antihistamines: It is a primary precursor for a range of well-known antihistamine medications. These include:
Cetirizine (e.g., Zyrtec)
Hydroxyzine (used for allergies and anxiety)
Meclizine (used for motion sickness and vertigo)
Chlorcyclizine
Research and Development: It is widely used in chemical and neuroscience research to explore new molecular designs and potential drug candidates. This includes studies in:
Developing novel anticancer agents and investigating their cytotoxicity.
Identifying potential inhibitors for specific biological targets, such as voltage-gated sodium channels (Nav1.7).
Synthesizing potential antipsychotic and antidepressant agents.
Analytical Standards: It is used as a reference standard in analytical chemistry, particularly for identifying and quantifying impurities in commercial preparations of hydroxyzine and cetirizine, as it is an inactive metabolite of these drugs.